Could Mars voyage cause Alzheimer's in astronauts?

Robots may still be our best bet for Mars missions.

(Credit:
NASA/JPL-Caltech/Malin Space Science Systems)

My brother has told me that if a manned Mars mission were seeking volunteers, he'd be the first in line, even if it meant never coming back. I wouldn't want him to go, but my desire to keep him Earth-bound is even more intense after checking out a new study on the impact of radiation on potential manned Mars missions.

A study published in PLOS One looks at the effects of galactic cosmic radiation on mice. Researchers exposed the mice to particle irradiation like that found in space. The result was cognitive impairment in line with the symptoms of Alzheimer's disease.

The study's lead author is Dr. M. Kerry O'Banion, a professor of neurobiology and anatomy at the University of Rochester Medical Center. Researchers exposed 29 male mice and 20 female mice to controlled doses of radiation at NASA's Space Radiation Laboratory at Brookhaven National Laboratory.

The mice were monitored for the next 3.5 months for the females and 6 months for the males. During this time, they underwent behavioral and memory testing, which showed a decrease in the mice's cognitive abilities.

"The doses used in this study are comparable to those astronauts will see on a mission to Mars, raising concerns about a heightened chance of debilitating dementia occurring long after the mission is over," the study states.

We may be a far cry away from sending people to Mars, but this study adds one more potential wrinkle to the many challenges ahead. It also lends some credence to those sci-fi stories about people going crazy in space. It could even explain why "Prometheus" was such a trainwreck. It wasn't the script, it was the space dementia.

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Hillary Clinton discharged from hospital

WASHINGTONSecretary of State Hillary Clinton was discharged from a New York hospital Wednesday, after spending 72 hours under observation following the discovery of a blood clot in her head, the State Department said.

In a statement, spokesperson Philippe Reines said: "Her medical team advised her that she is making good progress on all fronts, and they are confident she will make a full recovery. She's eager to get back to the office."

Clinton and her family thanked her medical team "for the excellent care she received," Reines said.

Earlier Wednesday, Clinton had been seen in public for the first time in three weeks when she walked out of the Harkness Eye Institute in New York City and into a secure van along with a smiling Bill and Chelsea Clinton and accompanied by a security detail, reports CBS News correspondent Margaret Brennan.

The State Department had said Secretary Clinton was active in speaking with staff and reviewing paperwork while she continued to recover at New York Presbyterian Hospital.

Clinton was admitted to a New York hospital Sunday and was treated with blood thinners to dissolve a clot in the vein behind the right ear. Doctors found the clot during a follow-up exam stemming from a concussion she suffered in early December. She has been hospitalized for around 72 hours, which is a window of time during which it is possible to establish the proper blood thinner dosage that would be required prior to discharge according to doctors.

Clinton's doctors say there was no neurological damage.

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Christie Calls Boehner's Sandy Decision 'Disgusting'

New Jersey Gov. Chris Christie said today that it was "disgusting" that the House adjourned without voting on a $60 billion relief package for the victims of superstorm Sandy and put the blame squarely on a fellow Republican -- House Speaker John Boehner.

Christie, who is considered a possible Republican presidential candidate four years from now, said there was "only one group to blame, the Republican Party and Speaker Boehner."

The blunt talking New Jersey governor joined a chorus of Republicans from New York and New Jersey fuming over his decision to pull the bill at the last minute.

Christie in an angry news conference decried the "selfishness and duplicity," the "palace intrigue," "the callous indifference to the people of our state."

"Unfortunately people are putting politics ahead of their responsibilities... You do the right thing. Enough with all the politics," he said.

Christie said that when it comes to natural disasters, "We respond as Americans, at least we did until last night... it was disgusting to watch."

"In our hour of desperate need, we've been left waiting for help six times longer than the victims of Katrina with no end in sight," said Christie. "Sixty-six days and counting, shame on you. Shame on Congress."

The governor said his four calls to Boehner Tuesday night went unanswered, but he said he spoke to the House speaker today. Christie would not disclose any details of the conversation, but clearly his anger over the no-vote was not mollified.

Following Christie's press conference Republican representatives from New York and New Jersey announced that the speaker promised a vote on the bill on Jan. 15.

"Getting critical aid to the victims of Hurricane Sandy should be the first priority in the new Congress, and that was reaffirmed today with members of the New York and New Jersey delegations," Boehner said in a statement released late this afternoon.

Rep. Peter King Blasts Speaker Boehner on House Floor Watch Video

Boos as House Adjourns Without Hurricane Sandy Relief Watch Video

'Fiscal Cliff' Deal Passes House Despite GOP Holdouts Watch Video

Rep. Peter King, R-NY, whop spent much of the day criticizing Boehner, met with the speaker this afternoon and was confident that the speaker would keep his word and hold a vote later this month and offered for the first time a reason for why the bill was pulled.

"[Boehner] said there was much confusion and so much fighting going on over the fiscal cliff bill it would be damaging to the Republican caucus" to have voted on the relief bill Tuesday night.

Lawmakers were initially told by Boehner, R-Ohio, that the relief bill would get a vote on Tuesday night following an eleventh hour vote on the fiscal cliff bill. But in an unexpected switch, Boehner refused to put the relief bill to a vote, leading to lawmakers from parties yelling on the floor of the House.

Congress historically has responded to natural disasters by promptly funding relief efforts. It took just 11 days to pass a relief package for victims of Hurricane Katrina in 2005. The Senate already passed its version of the bill that would replenish an emergency fund set to run out of cash next week and which will help repair subways and tunnels in New York City and rebuild parts of the New Jersey shore devastated by superstorm Sandy.

Time is particularly pressing, given that a new Congress will be sworn in Thursday. The Senate will therefore have to vote on the bill again before it comes to the House, which could be as late as February or March.

"This was a betrayal," Rep. Michael Grimm, R-N.Y., told ABC News.com. "It's just reprehensible. It's an indefensible error in judgment not have given relief to these people that are so devastated."

Rep. King, took the floor of the House and to the airwaves and aimed his outrage squarely at Boehner, accusing him plunging "a cruel knife in the back" of storm-ravaged residents "who don't have shelter, don't have food," he said during a House session this morning.

"This is not the United States. This should not be the Republican Party. This shouldn't not be the Republican leadership," King said on the floor of the House.

He made no attempt to hide his anger, suggesting that residents in New York and New Jersey should stop sending money to Republicans and even questioning whether he could remain a member of the party.

"Anyone who donates one cent to the Republican Congressional Campaign Committee should have their head examined," King, a staunch conservative and Republican congressman for 10 years, told CNN.

"They have written off New York and New Jersey. They've written me off…. Party loyalty, I'm over that. When your people are literally freezing in the winter… Then why should I help the Republican Party?" he added.

He said that Boehner refused to talk to Republican members from New York and New Jersey when they tried to ask him about the vote Tuesday night.

"He just decided to sneak off in the dark of night," King said.

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Central African Republic rebels halt advance, agree to peace talks

DAMARA, Central African Republic (Reuters) - Rebels in Central African Republic said they had halted their advance on the capital on Wednesday and agreed to start peace talks, averting a clash with regionally backed troops.

The Seleka rebels had pushed to within striking distance of Bangui after a three-week onslaught and threatened to oust President Francois Bozize, accusing him of reneging on a previous peace deal and cracking down on dissidents.

Their announcement on Wednesday gave the leader only a limited reprieve as the fighters told Reuters they might insist on his removal in the negotiations.

"I have asked our forces not to move their positions starting today because we want to enter talks in (Gabon's capital) Libreville for a political solution," said Seleka spokesman Eric Massi, speaking by telephone from Paris.

"I am in discussion with our partners to come up with proposals to end the crisis, but one solution could be a political transition that excludes Bozize," he said.

Bozize on Wednesday sacked his Army Chief of Staff and took over the defense minister's role from his son, Jean Francis Bozize, according to a decree read on national radio, a day after publicly criticizing the military for failing to repel the rebels.

The advance by Seleka, an alliance of mostly northeastern rebel groups, was the latest in a series of revolts in a country at the heart of one of Africa's most turbulent regions - and the most serious since the Chad-backed insurgency that swept Bozize to power in 2003.

Diplomatic sources have said talks organized by central African regional bloc ECCAS could start on January 10. The United States, the European Union and France have called on both sides to negotiate and spare civilians.

Central African Republic is one of the least developed countries in the world despite its deposits of gold, diamonds and other minerals. French nuclear energy group Areva mines the country's Bakouma uranium deposit - France's biggest commercial interest in its former colony.

RELIEF IN BANGUI

News of the rebel halt eased tension in Bangui, where residents had been stockpiling food and water and staying indoors after dark.

"They say they are no longer going to attack Bangui, and that's great news for us," said Jaqueline Loza in the crumbling riverside city.

ECCAS members Chad, Congo Republic, Gabon and Cameroon have sent hundreds of soldiers to reinforce CAR's army after a string of rebel victories since early December.

Gabonese General Jean Felix Akaga, commander of the regional force, said his troops were defending the town of Damara, 75 km (45 miles) north of Bangui and close to the rebel front.

"Damara is a red line not to be crossed ... Damara is in our control and Bangui is secure," he told Reuters. "If the rebellion decides to approach Damara, they know they will encounter a force that will react."

Soldiers armed with Kalashnikovs, rocket propelled grenade launchers and truck-mounted machineguns had taken up positions across the town, which was otherwise nearly-abandoned.

Some of the fighters wore turbans that covered their faces and had charms strung around their necks and arms meant to protect them against enemy bullets.

Chad's President Idriss Deby, one of Bozize's closest allies, had warned the rebels the regional force would confront them if they approached the town.

Chad provided training and equipment to the rebellion that brought Bozize to power by ousting then-president Ange Felix Patasse, who Chad accused of supporting Chadian dissidents.

Chad is also keen to keep a lid on instability in the territory close to its main oil export pipeline and has stepped in to defend Bozize against insurgents in the past.

A CAR government minister told Reuters the foreign troop presence strengthened Bozize's bargaining position ahead of the Libreville peace talks.

"The rebels are now in a position of weakness," the minister said, asking not to be named. "They should therefore stop imposing conditions like the departure of the president."

Central African Republic is one of a number of countries in the region where U.S. Special Forces are helping local soldiers track down the Lord's Resistance Army, a rebel group which has killed thousands of civilians across four nations.

France has a 600-strong force in CAR to defend about 1,200 of its citizens who live there.

Paris used air strikes to defend Bozize against a rebellion in 2006. But French President Francois Hollande turned down a request for more help, saying the days of intervening in other countries' affairs were over.

(Additional reporting by Paul-Marin Ngoupana in Bangui and Jon Herskovitz in Johannesburg; Writing by Richard Valdmanis; Editing by Andrew Heavens and Janet Lawrence)

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Amazon fends off Apple claim to "Appstore" name

OAKLAND: A federal judge on Wednesday rejected Apple's claim of false advertising for Amazon.com to refer to its online shop for mobile gadget applications as an "app store."

"Apple has failed to establish that Amazon made any false statement of fact that actually deceived or had the tendency to deceive a substantial segment of its audience," US District Judge Phyllis Hamilton said in her ruling.

"The mere use of 'Appstore' by Amazon to designate a site for viewing and downloading/purchasing apps cannot be construed as a representation that the nature, characteristics, or quality of the Amazon Appstore is the same as that of the Apple App Store."

Apple in 2008 launched its App Store, which is stocked with mini-programs for iPhones, iPads, and iPod touch devices.

Amazon in late 2011 opened its "Appstore," which sells applications tailored for Android-powered mobile devices for the Seattle, Washington-based retail giant's Kindle Fire tablets.

Apple sued Amazon, claiming its rival was engaging in false advertising as well as trademark infringement.

US officials are still considering Apple's application to trademark the term "App Store," but that did not deter the company from pressing its case in Hamilton's courtroom in the California city of Oakland.

Software titan Microsoft is among the companies that have weighed in against letting the Cupertino, California, company have a trademark giving it the exclusive right to call a mobile applications market an "app store."

- AFP/jc

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Instagram one month later: No hint of lingering troubles

New information from Web analytics firm Experian Hitwise suggests Instagram has recovered nicely from a seemingly disastrous privacy policy uproar last month.

For the 15 days since December 18, Instagram.com received more than 41.7 million total U.S. visits, an increase of 18 percent compared with the 15 days prior to the controversial proposed policy changes. The data was provided to CNET by Experian Marketing Services on request.

"The holidays see a spike in traffic as people are sharing more pictures than perhaps normal," Experian Marketing Services spokesman Matt Tatham told CNET, adding that the data doesn't include mobile traffic.

Facebook declined to provide official data or comment on this story.

Instagram members were alarmed in mid December when the Facebook-owned property announced it would include new language in its terms of service. The ambiguous language additions led many to believe that Instagram would be allowed to sell members' photos without their permission and without payment. The proposed changes set off a ruckus so loud that many users, influential celebrities included, said they'd be deleting their accounts.

Instagram co-founder Kevin Systrom responded by assuring members that their photos would not be sold, and he apologized for the confusion. The offending language has since been removed -- with Instagram reverting to its 2010 terms of service just before the holiday season kicked in -- but the damage was done, according to a widely circulated New York Post article claiming an Instagram exodus was in effect. That story cited third-party data from AppData -- which tracks Instagram users who log on through Facebook -- that showed a decline of close to 25 percent of the app's daily active users. An Instagram representative told CNET that the data was inaccurate.

If Instagram's Web traffic is any indicator, the photo-sharing app is weathering its privacy storm quite nicely, likely with the holidays to thank for its buoyancy. The 18 percent uptick in Web traffic is not reflective of user growth or indicative of any changes on mobile; it may represent nothing more than normal holiday fluctuations in sharing behaviors. Still, the 41.7 million visits Instagram accrued during the past 15 days speak to the continued relevance and growing footprint of a service that many turn to for sharing their most intimate moments.

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61 killed in post-celebration stampede in Ivory Coast

ABIDJAN, Ivory CoastA crowd stampeded after leaving a New Year's fireworks show early Tuesday in Ivory Coast's main city, killing 61 people — many of them children and teenagers — and injuring more than 200, rescue workers said.

Thousands had gathered at the Felix Houphouet Boigny Stadium in Abidjan's Plateau district to see the fireworks. It was only the second New Year's Eve fireworks display since peace returned to this West African nation after a bloody upheaval over presidential elections put the nation on the brink of civil war and turned this city into a battle zone.

With 2013 showing greater promise, people were in the mood to celebrate on New Year's Eve. Families brought children and they watched the rockets burst in the nighttime sky. But only an hour into the new year, as the crowds poured onto the Boulevard de la Republic after the show, something caused a stampede, said Col. Issa Sako of the fire department rescue team. How so many deaths occurred on the broad boulevard and how the tragedy started is likely to be the subject of an investigation.

Many of the younger ones in the crowd went down, trampled underfoot. Most of those killed were between 8 and 15 years old

"The flood of people leaving the stadium became a stampede which led to the deaths of more than 60 and injured more than 200," Sako told Ivory Coast state TV.

Desperate parents went to the city morgue, the hospital and to the stadium to try to find missing children. Mamadou Sanogo was searching for his 9-year-old son, Sayed.

"I have just seen all the bodies, but I cannot find my son," said a tearful Sanogo. "I don't know what to do."

State TV showed a woman sobbing in the back of an ambulance; another was bent over on the side of the street, apparently in pain; and another, barely conscious and wearing only a bra on her upper body, was hoisted by rescuers. There were also scenes of small children being treated in a hospital. One boy grimaced in pain and a girl with colored braids in her hair lay under a blanket with one hand bandaged. The death toll could rise, officials said.

After the sun came up, soldiers were patrolling the site that was littered with victims' clothes, shoes, torn sandals and other belongings. President Alassane Ouattara and his wife Dominique visited some of the injured in the hospital. Mrs. Ouattara leaned over one child who was on a bed in a crowded hospital ward and tried to console the youngster. The president pledged that the government would pay for their treatment, his office said.

The government organized the fireworks to celebrate Ivory Coast's peace, after several months of political violence in early 2011 following disputed elections.

This is not Ivory Coast's first stadium tragedy. In 2009, 22 people died and over 130 were injured in a stampede at a World Cup qualifying match at the Houphouet Boigny Stadium, prompting FIFA, soccer's global governing body, to impose a fine of tens of thousands of dollars on Ivory Coast's soccer federation. The stadium, which officially holds 35,000, was overcrowded at the time of the disaster.

A year later, two people were killed and 30 wounded in a stampede at a municipal stadium during a reggae concert in Bouake, the country's second-largest city. The concert was organized in the city, held by rebels at the time, to promote peace and reconciliation.

Ivory Coast is the world's largest cocoa producer, growing more than 37 percent of the world's annual crop of cocoa beans, which are used to make chocolate.

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House Hesitates, Cites Cliff Deal Spending

Top House Republicans today opposed a bipartisan compromise that passed the Senate in the wee hours of New Year's Day to avert the "fiscal cliff," amid concerns about the cost of spending and extending tax cuts in the plan.

If House Republicans tweak the legislation, as they seem likely to do, there's no clear path for its return to the Senate before a new Congress is sworn in Thursday.

GOP leaders emerged from a morning conference meeting disenchanted by the legislative package devised by Senate Minority Leader Mitch McConnell and Vice President Biden early this morning, with several insisting they cannot vote on it as it now stands.

"I do not support the bill," House Majority Leader Eric Cantor, R-Va., said as he left the meeting. "We're looking for the best path forward. No decisions have been made yet."

It's almost certain that Republicans will attempt to amend the bill in order to win over the support of more conservatives.

House Speaker John Boehner refused to comment on the meeting, but his spokesman said "the lack of spending cuts in the Senate bill was a universal concern amongst members in today's meeting."

"Conversations with members will continue throughout the afternoon on the path forward," Brendan Buck said in a statement.

As lawmakers wrestled with the legislation, the non-partisan Congressional Budget Office estimated that the bill's added spending combined with the cost of extending tax cuts for those making under $400,000 would actually add $3.9 trillion to the deficit over the next 10 years. The Joint Committee on Taxation reached a similar conclusion.

Bill Clark/Roll Call/Getty Images

Fiscal Cliff Countdown: Missing the Deadline Watch Video

Obama on Fiscal Cliff: 'Agreement Within Sight' Watch Video

The impasse once again raised the specter of sweeping tax hikes on all Americans and deep spending cuts' taking effect later this week.

"This is all about time, and it's about time that we brought this to the floor," House Minority Leader Nancy Pelosi said after emerging from a meeting with Democrats.

"It was a bill that was passed in the U.S. senate 89-8. Tell me when you've had that on a measure as controversial as this?" she said of the overwhelming vote.

Pelosi could not say, however, whether the measure had the backing of most House Democrats. "Our members are making their decisions now," she said.

Biden, who brokered the deal with McConnell, joined Democrats for a midday meeting on Capitol Hill seeking to shore up support for the plan.

While Congress technically missed the midnight Dec. 31 deadline to avert the so-called cliff, both sides have expressed eagerness to enact a post-facto fix before Americans go back to work and the stock market opens Wednesday.

"This may take a little while but, honestly, I would argue we should vote on it today," said Rep. Tom Cole, R-Okla., who sits on the Budget Committee. "We know the essential details and I think putting this thing to bed before the markets is important.

"We ought to take this deal right now and we'll live to fight another day, and it is coming very soon on the spending front."

The Senate passed legislation shortly after 2 a.m. that would extend current tax rates on 98 percent of Americans, raise taxes on the wealthiest earners and delay by two months the pending automatic spending cuts to defense and domestic programs, known as the "sequester."

The measure passed by an overwhelming majority vote of 89-8, boosting the prospects that enough House members would follow suit to make it law.

If the House amends the bill, however, the fragile compromise could get shattered. The Senate would need to reconvene to consider the changes.

A Senate Democratic leadership aide told ABC News, "we did our work, and McConnell's office said they were confident of House passage. All bets are off if they amend our bill."

Meanwhile, most Senators have already returned home, dismissed early this morning by Majority Leader Sen. Harry Reid.

"I've said all along our most important priority is protecting middle-class Americans, this legislation does that," Senate Majority Leader Harry Reid, D-Nev., said early this morning prior to the vote.

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At least 61 crushed to death in Ivory Coast stampede

ABIDJAN (Reuters) - At least 61 people were crushed to death in a stampede after a New Year's Eve fireworks display at a stadium in Ivory Coast's main city Abidjan early on Tuesday, officials said.

Witnesses said police had tried to control crowds around the Felix Houphouet-Boigny Stadium following the celebrations, triggering a panic in which scores were trampled.

"The estimate we can give right now is 49 people hospitalized ... and 61 people dead," said the chief of staff of Abidjan's fire department Issa Sacko.

Crying women searched for missing family members outside the stadium on Tuesday morning. The area was covered in patches of dried blood and abandoned shoes.

"My two children came here yesterday. I told them not to come but they didn't listen. They came when I was sleeping. What will I do?" said Assetou Toure, a cleaner.

Sanata Zoure, a market vendor injured in the incident, said New Year's revelers going home after watching the fireworks had been stopped by police near the stadium.

"We were walking with our children and we came upon barricades, and people started falling into each other. We were trampled with our children," she said.

Another witness said police arrived to control the crowd after a mob began chasing a pickpocket.

President Alassane Ouattara called the deaths a national tragedy and said an investigation was under way to find out what happened.

"I hope that we can determine what caused this drama so that we can ensure it never happens again," he said after visiting the injured in hospital.

The country, once a stable economic hub for West Africa, is struggling to recover from a 2011 civil war in which more than 3,000 people were killed.

Ivory Coast's security forces once were among the best trained in the region, but a decade of political turmoil and the 2011 war has left them in disarray.

At least 18 people were killed in another stampede during a football match in an Abidjan stadium in 2009.

(Reporting by Loucoumane Coulibaly and Alain Amontchi; Writing by Richard Valdmanis; Editing by Michael Roddy)

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Motorcycle bomb kills four in Pakistan's Karachi

KARACHI: A motorcycle bomb exploded Tuesday near the venue of a major political rally in Pakistan's largest city Karachi, killing four people and injuring 42 others, officials said.

The bombing appeared to be targeted at buses carrying supporters of the city's dominant political party, the Muttahida Qaumi Movement (MQM), which organised the rally attended by thousands of people.

"The latest report we have collected from hospitals said that four people have been killed and 42 are injured," provincial health minister Saghir Ahmad told AFP, updating the earlier toll of two dead and 25 injured.

Another health official at Karachi's Abbasi Shaheed hospital confirmed the new toll.

"The bomb was planted in a motorcycle," said Asif Ijaz, a senior police official.

Imran Shokat, a police spokesman in the southern Sindh province of which Karachi is the capital, said the motorcycle was parked in a congested neighbourhood near the venue of the rally.

"Bomb disposal experts are investigating but preliminary reports said it was a remote-controlled bomb," Shokat told AFP.

Karachi, the commercial capital of Pakistan with an estimated population of 18 million, is in the grip of a long-running wave of political and sectarian violence.

Its Arabian Sea port is used by the United States and NATO to ship supplies to the war in neighbouring, landlocked Afghanistan.

- AFP/jc

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